专利名称：METHOD FOR THE PREPARATION OF
CITALOPRAM
发明人：COTTICELLI, Giovanni,DI LERNIA,
Gianluca,MILANESI, Silvia
申请号：EP04791287.8申请日：20041022公开号：EP1682526B1公开日：20090114
摘要：A method for the preparation of citalopram and its pharmaceutically acceptablesalts is described; it's obtained starting from 5-cyanophthalide by reaction with a mixtureof 4fluorophenyl magnesium bromide and 3-dimethylaminopropyl magnesium chloride.The intermediate obtained is showed here-below: wherein X is an halogen, preferablychlorine or bromine, which is cyclized without any isolation.
申请人：ADORKEM TECHNOLOGY SPA
地址：IT
国籍：IT
代理机构：Pistolesi, Roberto
更多信息请下载全文后查看
因篇幅问题不能全部显示，请点此查看更多更全内容