Process and compositions for preparing particulate

专利名称：Process and compositions for preparing

particulate, bioactive or resorbablebiosilicates for use in the treatment of oralailments

发明人：Edgar Dutra Zanotto,Christian

Ravagnani,Oscar Peitl Filho,HeitorPanzeri,Elza Helena Guimares Lara

申请号：US10546365申请日：20040220

公开号：US20060251737A1公开日：20061109

摘要：A process for preparing particulate, bioactive and resorbable biosilicates fromvitreous plates or frits is described, which comprises thermally treating the vitreousplates or frits in a single or in two thermal treatment steps, at controlled temperaturesand times, and then milling the crystallized glass to obtain crystallized bioactive orresorbable biosilicate powders of desired bioactivity, free from sharp, cutting edges, thatin contact with body fluids produce a teeth-restoring hydroxycarbonate apatite layer orcan be gradually replaced by dental tissue and resorbed. Alternatively, a vitreous powderis first obtained, which is then thermally treated to yield the crystalline, bioactive orresorbable powder, which is free from sharp cutting edges. For different processconditions, different crystalline phases are obtained so that it is possible to obtain arange of bioactive or resorbable silicates that may be used as such or combined in thetreatment of different oral ailments such as dentine hypersensitivity, dental fissures and

xerostomy. The biosilicate particle size distribution is between 0.1 and 30 microns.

申请人：Edgar Dutra Zanotto,Christian Ravagnani,Oscar Peitl Filho,Heitor Panzeri,ElzaHelena Guimares Lara

地址：Sao Carlos BR,Sao Paulo BR,Sao Carlos BR,Ribeirao Preto BR,Ribeirao Preto BR

国籍：BR,BR,BR,BR,BR

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