您的当前位置:首页正文

ALTERED N-CADHERIN PROCESSING IN TUMOR CELLS BY FU

来源:个人技术集锦
专利内容由知识产权出版社提供

专利名称:ALTERED N-CADHERIN PROCESSING IN

TUMOR CELLS BY FURIN AND PROPROTEINCONVERTASE 5A (PC5A)

发明人:MARET, DEBORAH,COLMAN, DAVID,

R.,GRUZGLIN, EUGENIA,SEIDAH, NABIL

申请号:EP08843796申请日:20081103公开号:EP2211897A4公开日:20110413

摘要:The present invention relates to a method for diagnosis and/or prognosis ofcancer and for monitoring the progression of cancer and/or the therapeutic efficacy of ananti-cancer treatment in a subject by determining the molecular form of cadherin at thecell surface of cancer cells in the subject. The invention also relates to a method forpreventing, inhibiting or treating cancer or its metastasis in a subject by increasing theadhesive forms of cadherin and/or decreasing the non-adhesive forms of cadherin at thecell surface. The invention also relates to a method step of determining the expressionlevel of furin and proprotein convertase 5A (PC5A).

申请人:THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING / MCGILLUNIVERSITY,IRCM (INSTITUT DE RECHERCHES CLINIQUES DE MONTREAL),MOUNT SINAISCHOOL OF MEDICINE

更多信息请下载全文后查看

因篇幅问题不能全部显示,请点此查看更多更全内容