Product Name:CAS No.: Cat. No.:MWt:Formula:Purity :
Irbinitinib937263-43-9HY-16069480.52C26H24N8O2>98%
Solubility:DMSO 100 mg/ml
Mechanisms:
Pathways:JAK/STAT Signaling; Target:EGFR
Pathways:Protein Tyrosine Kinase/RTK; Target:EGFR
Biological Activity:
Irbinitinib(ARRY-380; ONT-380) is a potent and selective HER2 inhibitor with IC50 of 8 nM, equipotentagainst truncated p95-HER2, 500-fold more selective for HER2 versus EGFR.
References:
Caution: Not fully tested. For research purposes only
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