METHODS FOR PRODUCING VIRUS FOR VACCINE PRODUCTION

专利名称：METHODS FOR PRODUCING VIRUS FOR

VACCINE PRODUCTION

发明人：Raman RAO,Tatsuki SATO,Kaori ODA,Kuniaki

NAKAMURA,Takeshi NISHIHAMA

申请号：US16329654申请日：20170901

公开号：US20190194628A1公开日：20190627

专利附图：

摘要：The present disclosure relates to methods of producing Enterovirus C, e.g., forpoliomyelitis vaccine production. In some embodiments, the methods include adding

polysorbate to the cell culture medium during or prior to inoculation with the virusand/or culturing cells in a fixed bed bioreactor. Further provided herein is an EnterovirusC produced by the methods of production disclosed herein, as well as compositions,immunogenic compositions, and vaccines related thereto.

申请人：Takeda Vaccines, Inc.,Takeda Pharmaceutical Company Limited

地址：Cambridge MA US,Osaka JP

国籍：US,JP

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