METHOD AND KIT FOR ASSESSING VIABLE CELLS

专利名称：METHOD AND KIT FOR ASSESSING VIABLE

CELLS

发明人：SKINDERSØ, Mette Elena,SØRENSEN, Helle

Frobøse,KJÆRULFF, Søren

申请号：EP09776240.5申请日：20090713公开号：EP2312943A2公开日：20110427

摘要：The present invention provides simple, rapid methods and procedures foranalyzing cells, hereunder quantitative and qualitative assessment of cells, such asviability. The present invention relates to the use of various optionally substitutedreporter compounds particularly detectable upon their reaction with thiol-containingspecies present in higher concentrations in intact (e.g., living) cells than in non-intact (e.g.,dead, stressed and apoptotic) cells. The present invention also relates to the use ofvarious optionally substituted reporter compounds particularly detectable upon theirreaction with species present in intact and/or non-intact cells. Moreover, the presentinvention relates to the use of measuring techniques and/or instruments coupled withthe use of various optionally substituted reporter compounds. The invention furtherrelates to compositions used in methods for analyzing cells, such as a compositioncomprising N-(7-dimethylamino-4-methyl-3-coumarinyl)-maleimide (DACM).

申请人：Chemometec A/S

地址：Gydevang 3 3450 Allerød DK

国籍：DK

代理机构：Høiberg A/S

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